Journal article
Prevalence and Association of Perianal and Intra-Anal Warts with Composite High-Grade Squamous Intraepithelial Lesions Among Gay and Bisexual Men: Baseline Data from the Study of the Prevention of Anal Cancer
Sian L Goddard, David J Templeton, Kathy Petoumenos, Fengyi Jin, Richard J Hillman, Carmella Law, Jennifer M Roberts, Christopher K Fairley, Suzanne M Garland, Andrew E Grulich, Isobel Mary Poynten
AIDS PATIENT CARE AND STDS | MARY ANN LIEBERT, INC | Published : 2020
Abstract
Human papillomavirus (HPV) causes anal warts and anal squamous cell carcinoma (SCC). A higher incidence of anal cancer has been found among individuals previously diagnosed with anogenital warts. We aimed to investigate the association between anal warts and the presumed anal SCC precursor high-grade squamous intraepithelial lesion (HSIL), among participants in the Study of the Prevention of Anal Cancer (SPANC). SPANC was a longitudinal study of anal HPV infections and related lesions among gay and bisexual men (GBM) age 35 years and older, in Sydney, Australia. Anal cytology and high-resolution anoscopy were performed. Logistic regression was used to investigate the association between clin..
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Awarded by National Health and Medical Research Council
Awarded by Cancer Council New South Wales
Funding Acknowledgements
SPANC was supported by the National Health and Medical Research Council (Grant No. 568971) and the Cancer Council New South Wales (Grant No. 13-11). Cytologic testing materials were provided by Hologic Pty Ltd. The Kirby Institute is affiliated with the Faculty of Medicine, University of New South Wales, and funded by the Australian Government of Health and Aging.